I don't want anyone to give their secrets away, but I have no idea where to begin. I have the coach's recommended settings for now, but I doubt those are optimum. Any tips would be appreciated.

I have something like 20 saved weighting systems right now because I haven't cleaned mine up recently. :)

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Since I have no problems letting everyone know how crazy I am, here are my current weights. The one thing that I've noticed is that no matter your weighting system, elite players will continue to be elite. What this weighting system is doing is showing some nuance between players, but it's also showing how currently certain attributes like SP for a DE are way too overpowered. I have a DE in 2 with 20+ sacks who would be fourth on my depth chart if you just look at his improvable core skills:

QB
100 - Accuracy
75 - Look Off
50 - FoV
20 - INT, Arm, Release, Scramble
5 - Hard Count
1 - SP, AC, DI, Break, Carry, Avoid

RB
100 - Carry
75 - Avoid
50 - Break
25 - Catch
20 - SP, AC, INT, Courage
10 - ST, DI
1 - DI, Route, B&R

FB
100 - Run Block
75 - Pass Block
25 - Catch
20 - SP, AC, ST, Courage
10 - INT, DI
1 - B&R, Carry, Break, Avoid, Route

WR
100 - Route
75 - Catch
50 - B&R, Break, Carry
20 - SP, AC, INT, Courage
10 - DI
1 - Avoid, Run Block, ST

TE
100 - Run Block
75 - Catch
50 - Route, B&R
20 - SP, AC, INT, Courage, ST
10 - DI, Pass Block
1 - Carry, Avoid, Break Tackle

OT
100 - Pass
75 - Run
20 - AC, ST
10 - DI, IN

OG
100 - Run
75 - Pass
20 - AC, ST
10 - DI, IN

C
100 - Snap
75 - Pass, Run
20 - AC, ST
10 - DI, IN

DE
100 - Pass Rush, Tackle
75 - Run Def
20 - AC, SP, ST
10 - DI, IN, Punish
1 - Strip

DT
100 - Run Def, Tackle
75 - Pass Rush
20 - AC, ST
10 - DI, IN, Punish
1 - Strip

LB
100 - Tackle, Run Def
75 - Pass Rush
50 - Punish
20 - SP, AC, ST
10 - DI, IN
1 - Zone, M2M, Strip

CB
100 - Punish
75 - M2M, Tackle
50 - B&R, Run Def
20 - SP, AC
10 - ST, DI, IN
1 - Zone, Pass Rush

SS
100 - Punish
75 - Tackle, M2M
50 - Run Def, Zone
20 - SP, AC
10 - ST, DI, IN

FS
100 - Punish
75 - Tackle, Zone
50 - Run Def, M2M
20 - SP, AC
10 - ST, DI, IN