I looked at the 1st & Long gameplay weights - what the! They don't add up to 100. 1st & Long at the opponents 25 or closer, the gameplay weights add up to 208; 208, what the heck does that even mean?

Not sure specifically what you're talking about, but when setting tendencies the slider bars don't have to add up to 100. If they add up to more/less the computer just converts each to a percentage of the overall (you can see how it will break down percentage-wise along the top edge of the checkbox screen where you can copy those settings for locations, downs, short/medium/long, quarters, etc.)

And if I'm totally missing what you were commenting on, my apologies

no, that's what I was questioning.

It's not quite as disastrous as you might expect. Just be sure that all formations you don't actually use are set to 0. If the AI picks one of those, you get the dreaded Random Play.