Is 49 a good setting for fatigue?

I'm fairly new here.. still learning the mechanics myself. But IMO I feel like 49 COULD be good..or bad. Lower the value there faster they pull your tired players.. unless you have good depth at each position i feel like you should keep the value towards the higher (60). I personally run 55 for the most part depends on the team.

If anyone vet here has more detailed input of where they keep their values and why.. please speak up. As i said I'm still learning myself.

I like my settings between 40 & 50. It helps keep injuries low. Injuries still happen, mind you.

i set mine by position but usually around 55. I use over rides to keep guys fresh and take advantage of situations. Like a third down rb or and coverage lb, etc.